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Cat# BC-1613  Empirical Formula (Hill Notation) C17H18N2O6S

Synonym: α-Carboxybenzylpenicillin solution

Properties

Quality Level 200
sterility 0.2 μm filtered
form liquid
concentration 100 mg/mL in ethanol/water
solubility H2O: 100 mg/mL
ethanol: 100 mg/mL
suitability suitable for testing specifications (Bacteriostatic (cell type) E. Coli DH5a, result: pass)
Mode of action cell wall synthesis | interferes
antibiotic activity spectrum Gram-negative bacteria
Gram-positive bacteria
shipped in wet ice
storage temp. −20°C
SMILES string CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI 1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1
InChI key FPPNZSSZRUTDAP-UWFZAAFLSA-N

Safety Information

Symbol
Signal word
Danger
Hazard statements
Precautionary statements
Personal Protective Equipment
RIDADR
UN1170 – class 3 – PG 3 – Ethanol, solution
WGK Germany
WGK 2
Flash Point(F)
104.0 °F – closed cup – Not applicable
Flash Point(C)
40 °C – closed cup – Not applicable

Categories: ,

Description

 

Description

Ready Made Solution, 100 mg/mL in ethanol/water, 0.2 μm filtered

General description

Chemical structure: ß-lactam

Packaging

1 mL in glass bottle

Application

Carbenicillin is used for selection of Ampicillin-resistant transformed cells. It is used to study the role of penicillin-sensitive transpeptidases in the process cell wall biosynthesis.

Biochem/physiol Actions

Carbenicillin is an ampicillin analog with structure related to benzyl penicillin. It is effective against Gram-negative bacteria and exhibits limited activity against Gram-positive bacteria. Carbenicillin binds and inhibits the enzymes involved in the synthesis of bacterial cell wall. Since carbenicillin is less sensitive to β-lactamases than ampicillin, it is effective against ampicillin-resistant bacteria. It has superior stability at low pH and acts as a selection agent. Effective concentration of carbenicillin: 50 to 100 μg/ml.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

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