Rifampicin

suitable for plant cell culture, BioReagent, ≥97% (HPLC), crystalline

Synonym(s):

3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP

Empirical Formula (Hill Notation): C₄₃H₅₈N₄O₁₂

CAS Number: 13292-46-1

CAT Number: BC-2458

Molecular Weight: 822.94

EC Number: 236-312-0

NACRES: NA.72

PROPERTIES

product line BioReagent

Quality Level 200

assay ≥97% (HPLC)

form crystalline

technique(s) cell culture | plant: suitable

solubility chloroform: 50 mg/mL, clear

antibiotic activity spectrum

Gram-negative bacteria

Gram-positive bacteria

mycobacteria

application(s) agriculture

Mode of action protein synthesis | interferes

storage temp. −20°C

SMILES string

CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O

InChI

1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1

InChI key JQXXHWHPUNPDRT-WLSIYKJHSA-N

Categories: Cell Biology / Cell Culture, Lab Biochemicals, Lab Chemicals, Microbiology

Description
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Description

DESCRIPTION

General description

Chemical structure: macrolide

Application

Rifampicin, a rifamycin, is active against mycobacteria. Rifamycin, is also an inhibitor of chloroplast RNA polymerase and may be used to study chloroplast-level DNA transcription in plants.

Biochem/physiol Actions

Inhibits the assembly of DNA and protein into mature virus particles.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Product is sensitive to light and moisture. Store under inert gas.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 – P270 – P301 + P312 – P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 – Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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