Cefotaxime sodium salt

suitable for plant cell culture, BioReagent, powder or crystals

Synonym(s):

Cefotaxim sodium salt

CAT Number : BC-7039

CAS Number: 64485-93-4

Empirical Formula (Hill Notation): C₁₆H₁₆N₅NaO₇S₂

Molecular Weight: 477.45

Beilstein: 5711411

EC Number: 264-915-9

NACRES: NA.72

PROPERTIES

product line BioReagent

Quality Level 200

form powder or crystals

technique(s) cell culture | plant: suitable

color off-white to pale yellow

solubility H₂O: 10% ( )

antibiotic activity spectrum Gram-negative bacteria

Gram-positive bacteria

application(s) agriculture

Mode of action cell wall synthesis | interferes

storage temp. 2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key AZZMGZXNTDTSME-JUZDKLSSSA-M

Categories: Cell Biology / Cell Culture, Lab Biochemicals, Lab Chemicals, Microbiology

Description
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Description

DESCRIPTION

General description

Chemical structure: ß-lactam

Application

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria.In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes

Other Note:

Broad spectrum third generation cephalosporin antibiotic.

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H317 – H334

Precautionary Statements

P261 – P280 – P342 + P311

Hazard Classifications

Resp. Sens. 1 – Skin Sens. 1

Storage Class Code

13 – Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

General advice
First aiders need to protect themselves. Show this material safety data sheet to the doctor
in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.

Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands
and face after working with substance.

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